2-Chloro-4-fluorobenzoic acid
Name: 2-Chloro-4-fluorobenzoic acid; 4-Chloro-2-fluorobenzoic acid
English Name: 2-Chloro-4-fluorobenzoic acid
Molecular Formula: C7H4ClFO2
Molecular Weight: 174.56
CAS No: 2252-51-9
Structural Formula: 
1. Product Description
2-Chloro-4-fluorobenzoic acid is a white powdery solid.
Density: 1.4016 g/mL
Melting point: 181~183 ℃
Boiling point: 271.9±20 ℃
Flash point: 118.2 ℃
Insoluble in water, soluble in ethanol and ether.
It is mainly applied in organic synthesis.
2. Applications
It is an important intermediate for pharmaceuticals and pesticides, and also used in liquid crystal materials.
It can be used to prepare arylaminopyrazole benzamides, serving as oral non‑steroidal selective glucocorticoid receptor agonists.
It is also utilized for the synthesis of arginine vasopressin V2 receptor agonists and (4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-ylidene)acetamide derivatives.
3. Packaging
Fully sealed pressure-resistant packages of various specifications are available upon request.
During operation, isolate the product from air and moisture as much as possible, and use it immediately after opening.
4. Specification
Net weight: 25 kg per drum
5. Precautions
Store in a tightly sealed, cool and dry place.